ELEVATED HOMOCYSTEINE WORSE FOR MENTAL FUNCTION IN BIPOLAR
Bipolar disorder is associated with problems with learning (cognitive impairment). A study was carried out to determine if high blood levels of an amino acid called homocysteine were involved. Blood levels of homocysteine were found to be higher in 75 euthymic (neither elated nor depressed) bipolar patients than in 42 matched controls (people who are very similar but don't have bipolar). The researchers also found an association between higher levels of homocysteine and worse scores in intelligence tests that verbal learning, delayed memory and executive functions such as organising thoughts and prioritising.
Our Comment: Elevated homocysteine is lowered with B vitamins so can indicate a B vitamin deficiency.
For the abstract click here:
The Impact of Homocysteine Levels on Cognition in Euthymic Bipolar Patients: A Cross-Sectional Study, S Dittmann et al., J Clin Psychiatry 2008 Apr 8:e1-e8. [Epub ahead of print
Ref:food for the brain