Reporting in the Feb. 14, 2007, issue of Human Psychopharmacology, Turkish researchers from the Uludag University Medical Faculty tested 96 people who had major depression and 54 'normal' controls. Blood tests were measured markers of oxidation and antioxidant status. The researchers concluded that there was significantly higher levels of oxidation in the depressed people compared with the controls and in fact, according to some markers, the worse the oxidation, the worse the depression. Interestingly, since the study was designed to measure the effects of different antidepressant medications on oxidative-antioxidant systems, they concluded that the medications had no impact after six weeks.
Human Psychopharmacology: Clinical and Experimental, 2007; 22(2): 67-73
For the abstract, visit: 
http://www3.interscience.wiley.com/cgi-bin/abstract/114121813/ABSTRACT

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